本帖最后由 ranchgirl 于 2011-2-3 11:02 编辑
One interesting paper about the high blood pressure.
http://www.ncbi.nlm.nih.gov/pmc/ ... jcred00247-0031.pdf
Main result:
There will be no appreciable benefit (STROKE, CARDIAC MORBIDITY AND MORTALITY) to an individual patient from treating a diastolic pressure of less than 100 mg Hg.
In the paper:
DISADVANTAGES OF TREATING HIGH BLOOD PRESSURE
Some of the hypertension trials have shown that raised blood pressure often becomes normal with placebo treatment. In the Australian study 47% of the patients given placebo achieved a diastolic pressure of less than 95 mm Hg within three years, most within the first four months. In the MRC study, too, roughly 40% of the men and 45% of the women in the placebo group had a diastolic pressure of less than 90 mm Hg after one year. The modest benefits of active treatment shown in the MRC trial were bought at a considerable logistical price (695 000 invitations to attend for screening were sent out, 515 000 subjects screened, and 17 354 subjects entered into a five year study). A price was also paid in respect of drug side effects, and the prevention of strokes in a few patients entailed long term side effects ("mostly, but not all, minor") in many patients, such as gout, impotence, lethargy, and Raynaud's phenomenon. |